The speakers will need to be positioned so that they sit symmetrically between the walls of the room, otherwise the stereo image will be distorted. Putting speakers too close to corners tends to emphasize the bass in an unpredictable way, so try to place your speakers away from the room boundaries and make sure the setup is symmetrical, with the tweeters pointing at your head in your normal monitoring position.
Relatively small changes in speaker position can affect the sound quite significantly, so experiment with moving your speakers forward or backwards while some known commercial material is playing and aim for a smooth response, especially at the low end. If some bass notes seem louder than others, move the speakers around until the problem is minimized. Mounting the speakers on solid stands makes quite a difference.
See our MonitorStands page